Recovery of Prostaglandins in Human Cutaneous Inflammation
نویسندگان
چکیده
منابع مشابه
Prostaglandins and inflammation.
Prostaglandins are lipid autacoids derived from arachidonic acid. They both sustain homeostatic functions and mediate pathogenic mechanisms, including the inflammatory response. They are generated from arachidonate by the action of cyclooxygenase isoenzymes, and their biosynthesis is blocked by nonsteroidal antiinflammatory drugs, including those selective for inhibition of cyclooxygenase-2. De...
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Human milk contains many different components which interact locally in the gastrointestinal tract and stimulate some systemic functions. Among these substances are prostaglandins. We obtained samples of foremilk and hindmilk in 8 lactating women by manual expression before and after 9 a.m. and 9 p.m. on the 3rd day post partum. The following values were found for prostaglandin E2: foremilk, 16...
متن کاملProstaglandins in human milk
Nutritive and antimicrobial aspects of human milk have received considerable attention. However, another, as yet unproved role for breast milk has emerged in recent years: milk may contain factors which modify or supplement physiological functions in the neonate. For example milk lipase1 may assist in neonatal fat digestion, and hormones in milk-such as thyroxine2-may have biologically signific...
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Prostaglandins (PGs) are arachidonic acid metabolites produced by the action of the enzyme cyclooxygenase (COX). Although PGs are important mediators of inflammation in various diseases, they also are key factors in the physiological regulation of gastrointestinal and renal homeostasis. The finding that two distinct COX isoforms are responsible for PG synthesis has provided basis to the opposit...
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The mechanism of topically applied methyl nicotinate-induced local cutaneous erythema was studied in normal human subjects. Aqueous methyl nicotinate (0, 0.1, 1.0, 10.0, and 100 mmol/L) was applied to the volar forearms in quadruplicate after oral pretreatments with 25 mg doxepin hydrochloride, 600 mg ibuprofen, 50 mg indomethacin, 975 mg aspirin, and lactose placebo. The cutaneous vascular res...
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ژورنال
عنوان ژورنال: BMJ
سال: 1971
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.2.5756.258